2017年12月24日星期日

… Therapeutic Response In Murine Medulloblastoma Tumor Model Using Adenanthin And Transient Modulation Of The Blood-brain Barrier With Cadherin Peptide

… Therapeutic Response In Murine Medulloblastoma Tumor Model Using Adenanthin And Transient Modulation Of The Blood-brain Barrier With Cadherin Peptide

NH On, S Babu, R Omar, S Alrushaid, Y Wang… - Neuro …, 2017 - academic.oup.com
Abstract BACKGROUND Peroxiredoxin1 (PRDX1) is overexpressed in medulloblastoma
(MBL) causing resistance to therapy. Adenanthin (PRDX1 inhibitor) had been validated as a
therapeutic target in MBL. However, adenanthin does not cross the blood-brain barrier 


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