2018年3月6日星期二

A Direct Interaction Between Mitochondrial Proteins and Amyloid-β Peptide and its Significance for the Progression and Treatment of Alzheimer's Disease

A Direct Interaction Between Mitochondrial Proteins and Amyloid-β Peptide and its Significance for the Progression and Treatment of Alzheimer's Disease

O Benek, L Aitken, L Hroch, K Kuca… - Current Medicinal …, 2015 - ingentaconnect.com
The amyloid-β peptide (Aβ) has been associated with Alzheimer's disease (AD) for decades.
The original amyloid cascade hypothesis declared that the insoluble extracellular plaques
were responsible for Aβ toxicity. Later, this hypothesis has been updated and soluble


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