2018年3月28日星期三

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

R Kong, K Xu, T ZhouP AcharyaT Lemmin… - …, 2016 - science.sciencemag.org
The HIV-1 fusion peptide, comprising 15 to 20 hydrophobic residues at the N terminus of the
Env-gp41 subunit, is a critical component of the virus-cell entry machinery. Here, we report
the identification of a neutralizing antibody, N123-VRC34. 01, which targets the fusion …


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