2018年3月25日星期日

[HTML] Discovery and cardioprotective effects of the first non-peptide agonists of the G protein-coupled prokineticin receptor-1

[HTML] Discovery and cardioprotective effects of the first non-peptide agonists of the G protein-coupled prokineticin receptor-1

A Gasser, S Brogi, K Urayama, T Nishi, H Kurose… - PloS one, 2015 - journals.plos.org
Prokineticins are angiogenic hormones that activate two G protein-coupled receptors: PKR1
and PKR2. PKR1 has emerged as a critical mediator of cardiovascular homeostasis and
cardioprotection. Identification of non-peptide PKR1 agonists that contribute to myocardial …


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