Gallotannins and Tannic Acid: First Chemical Syntheses and In Vitro Inhibitory Activity on Alzheimer's Amyloid β‐Peptide Aggregation

Gallotannins and Tannic Acid: First Chemical Syntheses and In Vitro Inhibitory Activity on Alzheimer's Amyloid β‐Peptide Aggregation

T Sylla, L Pouységu, G Da Costa, D Deffieux… - Angewandte …, 2015 - Wiley Online Library

Abstract The screening of natural products in the search for new lead compounds against
Alzheimer's disease has unveiled several plant polyphenols that are capable of inhibiting
the formation of toxic β-amyloid fibrils. Gallic acid based gallotannins are among these …

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