Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa

Influence of hydrophobic residues on the activity of the antimicrobial peptide magainin 2 and its synergy with PGLa

E Strandberg, J Zerweck, D Horn, G Pritz… - Journal of Peptide …, 2015 - Wiley Online Library

Abstract Magainin 2 (MAG2) and PGLa are two related antimicrobial peptides found in the
skin of the African frog Xenopus laevis with a pronounced synergistic activity, which act by
permeabilizing bacterial membranes. To probe the influence of hydrophobic peptide–lipid …

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