2018年3月26日星期一

von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII

von Willebrand factor binds to the surface of dendritic cells and modulates peptide presentation of factor VIII

N Sorvillo, RB Hartholt, E Bloem, M Sedek… - …, 2015 - haematologica.org
It has been proposed that von Willebrand Factor might affect factor VIII immunogenicity by
reducing factor VIII uptake by antigen presenting cells. Here, we investigate the interaction of
recombinant von Willebrand Factor with immature monocyte-derived dendritic cells using …


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