Synthetic TRP2 long-peptide and α-galactosylceramide formulated into cationic liposomes elicit CD8+ T-cell responses and prevent tumour progression

Synthetic TRP2 long-peptide and α-galactosylceramide formulated into cationic liposomes elicit CD8+ T-cell responses and prevent tumour progression

S Neumann, K Young, B Compton, R Anderson… - Vaccine, 2015 - Elsevier

Abstract The lipid antigen α-galactosylceramide (α-GalCer) is a potent activator of invariant
natural killer T-cells (iNKT cells) and can stimulate cytotoxic and anti-tumour immune
responses. However optimal responses appear to be induced by α-GalCer when cell-based …

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