[HTML] Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion
T Delong, TA Wiles, RL Baker, B Bradley… - …, 2016 - science.sciencemag.org
T cell–mediated destruction of insulin-producing β cells in the pancreas causes type 1
diabetes (T1D). CD4 T cell responses play a central role in β cell destruction, but the identity
of the epitopes recognized by pathogenic CD4 T cells remains unknown. We found that …
diabetes (T1D). CD4 T cell responses play a central role in β cell destruction, but the identity
of the epitopes recognized by pathogenic CD4 T cells remains unknown. We found that …
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