A CRISPR screen defines a signal peptide processing pathway required by flaviviruses
Abstract Flaviviruses infect hundreds of millions of people annually, and no antiviral therapy
is available 1, 2. We performed a genome-wide CRISPR/Cas9-based screen to identify host
genes that, when edited, resulted in reduced flavivirus infection. Here, we validated nine …
is available 1, 2. We performed a genome-wide CRISPR/Cas9-based screen to identify host
genes that, when edited, resulted in reduced flavivirus infection. Here, we validated nine …
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