2018年3月9日星期五

Activable cell-penetrating peptide conjugated prodrug for tumor targeted drug delivery

Activable cell-penetrating peptide conjugated prodrug for tumor targeted drug delivery

H Cheng, JY Zhu, XD Xu, WX Qiu, Q Lei… - … applied materials & …, 2015 - ACS Publications
In this paper, an activable cell-penetrating peptide (CR8G3PK6, ACPP) with a shielding
group of 2, 3-dimethylmaleic anhydride (DMA) was conjugated with antitumor drug
doxorubicin (DOX) to construct a novel prodrug (DOX-ACPP-DMA) for tumor targeted drug


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