2018年3月14日星期三

Exploring the Alzheimer amyloid-β peptide conformational ensemble: A review of molecular dynamics approaches

Exploring the Alzheimer amyloid-β peptide conformational ensemble: A review of molecular dynamics approaches

L Tran, T Ha-Duong - Peptides, 2015 - Elsevier
Abstract Alzheimer's disease is one of the most common dementia among elderly
worldwide. There is no therapeutic drugs until now to treat effectively this disease. One main
reason is due to the poorly understood mechanism of Aβ peptide aggregation, which plays a


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