Hemichannels are required for amyloid β-peptide-induced degranulation and are activated in brain mast cells of APPswe/PS1dE9 mice
PA Harcha, A Vargas, C Yi, AA Koulakoff… - Journal of …, 2015 - Soc Neuroscience
Mast cells (MCs) store an array of proinflammatory mediators in secretory granules that are
rapidly released upon activation by diverse conditions including amyloid beta (Aβ) peptides.
In the present work, we found a rapid degranulation of cultured MCs through a pannexin1
rapidly released upon activation by diverse conditions including amyloid beta (Aβ) peptides.
In the present work, we found a rapid degranulation of cultured MCs through a pannexin1
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