2018年3月5日星期一

[HTML] Anti-human α-synuclein N-terminal peptide antibody protects against dopaminergic cell death and ameliorates behavioral deficits in an AAV-α-synuclein rat …

[HTML] Anti-human α-synuclein N-terminal peptide antibody protects against dopaminergic cell death and ameliorates behavioral deficits in an AAV-α-synuclein rat …

M Shahaduzzaman, K Nash, C Hudson, M Sharif… - PloS one, 2015 - journals.plos.org
The protein α-synuclein (α-Syn) has a central role in the pathogenesis of Parkinson's
disease (PD) and immunotherapeutic approaches targeting this molecule have shown
promising results. In this study, novel antibodies were generated against specific peptides


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