[HTML] Mechanistic investigation of aziridine aldehyde-driven peptide macrocyclization: the imidoanhydride pathway
S Zaretsky, JL Hickey, J Tan, D Pichugin… - Chemical …, 2015 - pubs.rsc.org
Aziridine aldehyde dimers, peptides, and isocyanides participate in a multicomponent
reaction to yield peptide macrocycles. We have investigated the selectivity and kinetics of
this process and performed a detailed analysis of its chemoselectivity. While the reactants
reaction to yield peptide macrocycles. We have investigated the selectivity and kinetics of
this process and performed a detailed analysis of its chemoselectivity. While the reactants
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