[HTML] Nociceptin/orphanin FQ peptide receptor antagonist JTC‐801 reverses pain and anxiety symptoms in a rat model of post‐traumatic stress disorder
Y Zhang, CD Simpson‐Durand… - British journal of …, 2015 - Wiley Online Library
Background and Purpose Single-prolonged stress (SPS), a rat model of post-traumatic
stress disorder (PTSD), also induces long-lasting hyperalgesia associated with
hypocortisolism and elevated nociceptin/orphanin FQ (N/OFQ) levels in serum and CSF.
stress disorder (PTSD), also induces long-lasting hyperalgesia associated with
hypocortisolism and elevated nociceptin/orphanin FQ (N/OFQ) levels in serum and CSF.
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