2018年3月13日星期二

Il-6 antibody and RGD peptide conjugated poly (amidoamine) dendrimer for targeted drug delivery of HeLa cells

Il-6 antibody and RGD peptide conjugated poly (amidoamine) dendrimer for targeted drug delivery of HeLa cells

SL Mekuria, TA Debele, HY Chou… - The Journal of Physical …, 2015 - ACS Publications
In this study, PAMAM dendrimer (G4. 5) was conjugated with two targeting moieties, IL-6
antibody and RGD peptide (G4. 5-IL6 and G4. 5-RGD conjugates). Doxorubicin anticancer
drug was physically loaded onto G4. 5-IL6 and G4. 5-RGD with the encapsulation efficiency


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