Peptide immunoaffinity enrichment and targeted mass spectrometry enables multiplex, quantitative pharmacodynamic studies of phospho-signaling
JR Whiteaker, L Zhao, P Yan, RG Ivey… - Molecular & cellular …, 2015 - ASBMB
Abstract In most cell signaling experiments, analytes are measured one Western blot lane at
a time in a semiquantitative and often poorly specific manner, limiting our understanding of
network biology and hindering the translation of novel therapeutics and diagnostics. We
a time in a semiquantitative and often poorly specific manner, limiting our understanding of
network biology and hindering the translation of novel therapeutics and diagnostics. We
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