Pharmaceutical optimization of peptide toxins for ion channel targets: potent, selective, and long-lived antagonists of Kv1. 3
JK Murray, YX Qian, B Liu, R Elliott, J Aral… - Journal of medicinal …, 2015 - ACS Publications
To realize the medicinal potential of peptide toxins, naturally occurring disulfide-rich
peptides, as ion channel antagonists, more efficient pharmaceutical optimization
technologies must be developed. Here, we show that the therapeutic properties of multiple
peptides, as ion channel antagonists, more efficient pharmaceutical optimization
technologies must be developed. Here, we show that the therapeutic properties of multiple
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