2018年3月13日星期二

Phosphothreonine as a Catalytic Residue in Peptide‐Mediated Asymmetric Transfer Hydrogenations of 8‐Aminoquinolines

Phosphothreonine as a Catalytic Residue in Peptide‐Mediated Asymmetric Transfer Hydrogenations of 8‐Aminoquinolines

CR Shugrue, SJ Miller - Angewandte Chemie, 2015 - Wiley Online Library
Abstract Phosphothreonine (pThr) was found to constitute a new class of chiral phosphoric
acid (CPA) catalyst upon insertion into peptides. To demonstrate the potential of these
phosphopeptides as asymmetric catalysts, enantioselective transfer hydrogenations of a


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