2018年3月21日星期三

Radiosynthesis and micro-SPECT analysis of triazole-based RGD integrin ligands as non-peptide molecular imaging probes for angiogenesis

Radiosynthesis and micro-SPECT analysis of triazole-based RGD integrin ligands as non-peptide molecular imaging probes for angiogenesis

F Bianchini, P Fabbrizzi, G Menchi, S Raspanti… - Bioorganic & medicinal …, 2015 - Elsevier
Abstract Taking advantage of click chemistry, we synthesized triazole-containing RGD
peptidomimetics capable of binding to α v β 3 integrin with diverse potency, and selected
125 I-labeled compounds proved to interact in vitro and in vivo with α v β 3 integrin …


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