Short hydrophobic peptides with cyclic constraints are potent glucagon-like peptide-1 receptor (GLP-1R) agonists
Cyclic constraints are incorporated into an 11-residue analogue of the N-terminus of
glucagon-like peptide-1 (GLP-1) to investigate effects of structure on agonist activity.
Cyclization through linking side chains of residues 2 and 5 or 5 and 9 produced agonists at
glucagon-like peptide-1 (GLP-1) to investigate effects of structure on agonist activity.
Cyclization through linking side chains of residues 2 and 5 or 5 and 9 produced agonists at
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