The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage‐gated sodium channels via a large β‐hairpin loop

The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage‐gated sodium channels via a large β‐hairpin loop

NS Bende, S Dziemborowicz, V Herzig… - The FEBS …, 2015 - Wiley Online Library

Abstract Spider venoms contain a plethora of insecticidal peptides that act on neuronal ion
channels and receptors. Because of their high specificity, potency and stability, these
peptides have attracted much attention as potential environmentally friendly insecticides …

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