Tumor Necrosis Factor α Decreases Glucagon-Like Peptide-2 Expression by Up-Regulating G-Protein–Coupled Receptor 120 in Crohn Disease
T Tsukahara, K Watanabe… - … American journal of …, 2015 - hemonc.theclinics.com
Glucagon-like peptide (GLP)-2, secreted by L cells in the small intestine, has anti-
inflammatory effects in the gastrointestinal tract. A GLP-2 analogue has been an effective
treatment for Crohn disease (CD). G-protein–coupled receptor (GPR) 40 and GPR120 are
inflammatory effects in the gastrointestinal tract. A GLP-2 analogue has been an effective
treatment for Crohn disease (CD). G-protein–coupled receptor (GPR) 40 and GPR120 are
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