An insulin-IAPP hybrid peptide is an endogenous antigen for CD4 T cells in the non-obese diabetic mouse
TA Wiles, T Delong, RL Baker, B Bradley… - Journal of …, 2017 - Elsevier
Abstract BDC-6.9, a diabetogenic CD4 T cell clone isolated from a non-obese diabetic
(NOD) mouse, responds to pancreatic islet cells from NOD but not BALB/c mice. We recently
reported that a hybrid insulin peptide (HIP), 6.9 HIP, formed by linkage of an insulin C-
(NOD) mouse, responds to pancreatic islet cells from NOD but not BALB/c mice. We recently
reported that a hybrid insulin peptide (HIP), 6.9 HIP, formed by linkage of an insulin C-
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