2017年12月23日星期六

CIGB-300, an anti-CK2 peptide, inhibits angiogenesis, tumor cell invasion and metastasis in lung cancer models

CIGB-300, an anti-CK2 peptide, inhibits angiogenesis, tumor cell invasion and metastasis in lung cancer models

FB Acero, CS Capobianco, J Garona, SM Cirigliano… - Lung Cancer, 2017 - Elsevier
Objectives Casein kinase 2 (CK2) is overexpressed in several types of cancer. It has more
than 300 substrates mainly involved in DNA reparation and replication, chromatin
remodeling and cellular growth. In recent years CK2 became an interesting target for 


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