Discovery and molecular interaction studies of a highly stable, tarantula peptide modulator of acid-sensing ion channel 1
SY Er, B Cristofori-Armstrong, P Escoubas, LD Rash - Neuropharmacology, 2017 - Elsevier
Abstract Acute pharmacological inhibition of acid-sensing ion channel 1a (ASIC1a) is
efficacious in rodent models in alleviating symptoms of neurological diseases such as stroke
and multiple sclerosis. Thus, ASIC1a is a promising therapeutic target and selective ligands
efficacious in rodent models in alleviating symptoms of neurological diseases such as stroke
and multiple sclerosis. Thus, ASIC1a is a promising therapeutic target and selective ligands
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