Cyclic peptide therapeutics: past, present and future
A Zorzi, K Deyle, C Heinis - Current Opinion in Chemical Biology, 2017 - Elsevier
Cyclic peptides combine several favorable properties such as good binding affinity, target
selectivity and low toxicity that make them an attractive modality for the development of
therapeutics. Over 40 cyclic peptide drugs are currently in clinical use and around one new
selectivity and low toxicity that make them an attractive modality for the development of
therapeutics. Over 40 cyclic peptide drugs are currently in clinical use and around one new
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