Preclinical evaluation of taxane-binding peptide-modified polymeric micelles loaded with docetaxel in an orthotopic breast cancer mouse model

Preclinical evaluation of taxane-binding peptide-modified polymeric micelles loaded with docetaxel in an orthotopic breast cancer mouse model

J Logie, AN Ganesh, AM Aman, RS Al-awar… - Biomaterials, 2017 - Elsevier

Abstract We developed a novel taxane-binding peptide (TBP) modified, biodegradable
polymeric micelle that overcomes limitations of drug loading and poor serum stability
typically seen with particle delivery, leading to enhanced pharmacokinetics and tumor 

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