Acetone‐Linked Peptides: A Convergent Approach for Peptide Macrocyclization and Labeling
N Assem, DJ Ferreira, DW Wolan… - Angewandte Chemie …, 2015 - Wiley Online Library
Abstract Macrocyclization is a broadly applied approach for overcoming the intrinsically
disordered nature of linear peptides. Herein, it is shown that dichloroacetone (DCA)
enhances helical secondary structures when introduced between peptide nucleophiles,
disordered nature of linear peptides. Herein, it is shown that dichloroacetone (DCA)
enhances helical secondary structures when introduced between peptide nucleophiles,
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