An efficient Fmoc‐SPPS approach for the generation of thioester peptide precursors for use in native chemical ligation
JB Blanco‐Canosa, PE Dawson - … Chemie International Edition, 2008 - Wiley Online Library
The straightforward C-terminal modification of peptides assembled on a solid support
remains a significant challenge in peptide and protein chemistry. In particular, C-terminal
thioester peptides are important intermediates for the generation of active esters, amides
remains a significant challenge in peptide and protein chemistry. In particular, C-terminal
thioester peptides are important intermediates for the generation of active esters, amides
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