2018年2月7日星期三

Chemoenzymatic synthesis of thiazolyl peptide natural products featuring an enzyme-catalyzed formal [4+ 2] cycloaddition

Chemoenzymatic synthesis of thiazolyl peptide natural products featuring an enzyme-catalyzed formal [4+ 2] cycloaddition

WJ Wever, JW Bogart, JA Baccile… - Journal of the …, 2015 - ACS Publications
Thiocillins from Bacillus cereus ATCC 14579 are members of the well-known thiazolyl
peptide class of natural product antibiotics, the biosynthesis of which has recently been
shown to proceed via post-translational modification of ribosomally encoded precursor


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