[HTML] The repertoire of T cells shaped by a single MHC/peptide ligand
L Ignatowicz, J Kappler, P Marrack - Cell, 1996 - Elsevier
Abstract Although the thymus produces many immature thymocytes, few of these cells
mature. Positive selection has been thought to limit thymocyte development. In thymuses
expressing a single MHC/peptide combination, however, surprisingly large numbers of
mature. Positive selection has been thought to limit thymocyte development. In thymuses
expressing a single MHC/peptide combination, however, surprisingly large numbers of
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