2018年2月7日星期三

[HTML] A subset of human bromodomains recognizes butyryllysine and crotonyllysine histone peptide modifications

[HTML] A subset of human bromodomains recognizes butyryllysine and crotonyllysine histone peptide modifications

EM Flynn, OW Huang, F Poy, M Oppikofer, SF Bellon… - Structure, 2015 - Elsevier
Summary Bromodomains are epigenetic readers that are recruited to acetyllysine residues
in histone tails. Recent studies have identified non-acetyl acyllysine modifications, raising
the possibility that these might be read by bromodomains. Profiling the nearly complete


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