[HTML] A viral ER-resident glycoprotein inactivates the MHC-encoded peptide transporter
H Hengel, JO Koopmann, T Flohr, W Muranyi… - Immunity, 1997 - Elsevier
Abstract Human cytomegalovirus inhibits peptide import into the endoplasmic reticulum (ER)
by the MHC-encoded TAP peptide transporter. We identified the open reading frame US6 to
mediate this effect. Expression of the 21 kDa US6 glycoprotein in human cytomegalovirus–
by the MHC-encoded TAP peptide transporter. We identified the open reading frame US6 to
mediate this effect. Expression of the 21 kDa US6 glycoprotein in human cytomegalovirus–
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