Prodrug approaches to the improved delivery of peptide drugs.
W Wang, J Jiang, CE Ballard, B Wang - Current pharmaceutical …, 1999 - europepmc.org
Abstract Undesirable pharmaceutical and biopharmaceutical properties, which include low
water solubility, poor stability, and low permeability through biological membrane barriers,
often hinder the clinical development of biologically active peptides. Finding solutions to
water solubility, poor stability, and low permeability through biological membrane barriers,
often hinder the clinical development of biologically active peptides. Finding solutions to
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