2018年2月6日星期二

The TCR's sensitivity to self peptide–MHC dictates the ability of naive CD8+ T cells to respond to foreign antigens

The TCR's sensitivity to self peptide–MHC dictates the ability of naive CD8+ T cells to respond to foreign antigens

RB Fulton, SE Hamilton, Y Xing, JA Best… - Nature …, 2015 - nature.com
Abstract The strength with which complexes of self peptide and major histocompatibility
complex (MHC) proteins are recognized by the T cell antigen receptor (TCR) dictates the
homeostasis of naive CD8+ T cells, but its effect on reactivity to foreign antigens is


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