Amyloid β peptide directly impairs pineal gland melatonin synthesis and melatonin receptor signaling through the ERK pathway
Abstract Melatonin is the hormone produced by the pineal gland known to regulate
physiologic rhythms and to display immunomodulatory and neuroprotective properties. It has
been reported that Alzheimer disease patients show impaired melatonin production and
physiologic rhythms and to display immunomodulatory and neuroprotective properties. It has
been reported that Alzheimer disease patients show impaired melatonin production and
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