2018年3月13日星期二

Dual inhibitors of the dengue and West Nile virus NS2B–NS3 proteases: synthesis, biological evaluation and docking studies of novel peptide-hybrids

Dual inhibitors of the dengue and West Nile virus NS2B–NS3 proteases: synthesis, biological evaluation and docking studies of novel peptide-hybrids

AB Lima, MAM Behnam, Y El Sherif, C Nitsche… - Bioorganic & medicinal …, 2015 - Elsevier
Abstract Dengue virus (DENV) and West Nile virus (WNV) are mosquito-borne arboviruses
responsible for causing acute systemic diseases and severe health conditions in humans.
The discovery of therapies capable to prevent infections or treat infected individuals remains


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