Force-Regulated In Situ TCR–Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells
J Hong, SP Persaud, S Horvath, PM Allen… - The Journal of …, 2015 - Am Assoc Immnol
We have recently shown that two-dimensional (2D) and force-regulated kinetics of TCR–
peptide-bound MHC class I (pMHC-I) interactions predict responses of CD8+ T cells. To test
whether these findings are applicable to CD4+ T cells, we analyzed the in situ 3. L2 TCR–
peptide-bound MHC class I (pMHC-I) interactions predict responses of CD8+ T cells. To test
whether these findings are applicable to CD4+ T cells, we analyzed the in situ 3. L2 TCR–
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