Peptide deformylase: a new target in antibacterial, antimalarial and anticancer drug discovery
JN Sangshetti, FA Kalam Khan… - Current medicinal …, 2015 - ingentaconnect.com
Peptide deformylase (PDF) is a class of metalloenzyme responsible for catalyzing the
removal of the N-formyl group from N-terminal methionine following translation. PDF
inhibitors are moving into new phase of drug development. Initially, PDF was considered as
removal of the N-formyl group from N-terminal methionine following translation. PDF
inhibitors are moving into new phase of drug development. Initially, PDF was considered as
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