Fine Tuning of β‐Peptide Foldamers: a Single Atom Replacement Holds Back the Switch from an 8‐Helix to a 12‐Helix

Fine Tuning of β‐Peptide Foldamers: a Single Atom Replacement Holds Back the Switch from an 8‐Helix to a 12‐Helix

A Altmayer‐Henzien, V Declerck… - Angewandte Chemie …, 2015 - Wiley Online Library

Cyclic homologated amino acids are important building blocks for the construction of helical
foldamers. N‐aminoazetidine‐2‐carboxylic acid (AAzC), an aza analogue of trans‐2‐
aminocyclobutanecarboxylic acid (tACBC), displays a strong hydrazino turn conformational …

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