[HTML] dNP2 is a blood–brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis
S Lim, WJ Kim, YH Kim, S Lee, JH Koo, JA Lee… - Nature …, 2015 - nature.com
Central nervous system (CNS)-infiltrating effector T cells play critical roles in the
development and progression of multiple sclerosis (MS). However, current drugs for MS are
very limited due to the difficulty of delivering drugs into the CNS. Here we identify a cell …
development and progression of multiple sclerosis (MS). However, current drugs for MS are
very limited due to the difficulty of delivering drugs into the CNS. Here we identify a cell …
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