2017年12月22日星期五

Sequence-specific model for peptide retention time prediction in strong cation exchange chromatography

Sequence-specific model for peptide retention time prediction in strong cation exchange chromatography

D Gussakovsky, H Neustaeter, V Spicer… - Analytical …, 2017 - ACS Publications
The development of a peptide retention prediction model for strong cation exchange (SCX)
separation on a Polysulfoethyl A column is reported. Off-line 2D LC-MS/MS analysis (SCX-
RPLC) of S. cerevisiae whole cell lysate was used to generate a retention dataset of∼ 30 


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