A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1β processing and release
A Elssner, M Duncan, M Gavrilin… - The Journal of …, 2004 - Am Assoc Immnol
The release of IL-1β is a tightly controlled process that requires induced synthesis of the
precursor pro-IL-1β and a second stimulus that initiates cleavage and secretion of mature IL-
1β. Although ATP as a second stimulus potently promotes IL-1β maturation and release via
precursor pro-IL-1β and a second stimulus that initiates cleavage and secretion of mature IL-
1β. Although ATP as a second stimulus potently promotes IL-1β maturation and release via
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