2018年2月3日星期六

Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor

Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor

JM Roch, E Masliah, AC Roch-Levecq… - Proceedings of the …, 1994 - National Acad Sciences
Abstract The secreted form (sAPP) of the Alzheimer amyloid beta/A4 protein precursor (APP)
has been shown to be involved in the in vitro regulation of fibroblast growth and neurite
extension from neuronal cells. The active site of sAPP responsible for these functions is


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