Brain natriuretic peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases
T Tsuruda, G Boerrigter, BK Huntley, JA Noser… - Circulation …, 2002 - Am Heart Assoc
Cardiac fibroblasts (CFs) produce extracellular matrix proteins and participate in the
remodeling of the heart. It is unknown if brain natriuretic peptide (BNP) is synthesized by
CFs and if BNP participates in the regulation of extracellular matrix turnover. In this study, we
remodeling of the heart. It is unknown if brain natriuretic peptide (BNP) is synthesized by
CFs and if BNP participates in the regulation of extracellular matrix turnover. In this study, we
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