Non-peptide fibrinogen receptor antagonists. 1. Discovery and design of exosite inhibitors
GD Hartman, MS Egbertson, W Halczenko… - Journal of medicinal …, 1992 - ACS Publications
When a blood vessel is injured, either by the acute damage of wounding or clinical
interventions, or more chronically by the pathophysiological processes of atherosclerosis,
platelets are activated to adhere to the disrupted surface and to each other. This activation,
interventions, or more chronically by the pathophysiological processes of atherosclerosis,
platelets are activated to adhere to the disrupted surface and to each other. This activation,
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