2018年2月6日星期二

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients

H Benham, HJ Nel, SC Law, AM Mehdi… - Science translational …, 2015 - stm.sciencemag.org
In animals, immunomodulatory dendritic cells (DCs) exposed to autoantigen can suppress
experimental arthritis in an antigen-specific manner. In rheumatoid arthritis (RA), disease-
specific anti–citrullinated peptide autoantibodies (ACPA or anti-CCP) are found in the serum


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