Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old …
R Perfetti, JIE Zhou, ME Doyle, JM Egan - Endocrinology, 2000 - academic.oup.com
Abstract Glucose homeostasis in mammals is maintained by insulin secretion from the β-
cells of the islets of Langerhans. Type 2 diabetes results either from primary β-cell failure
alone and/or a failure to secrete enough insulin to overcome insulin resistance. Here, we
cells of the islets of Langerhans. Type 2 diabetes results either from primary β-cell failure
alone and/or a failure to secrete enough insulin to overcome insulin resistance. Here, we
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